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Invitrogen™ COPS6 Monoclonal Antibody (2H5)
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Catalog No. PIMA521211
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100 μg
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PIMA521211 100 μg
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Catalog No. PIMA521211 Supplier Invitrogen™ Supplier No. MA521211
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Description

Mouse Monoclonal Antibody

Peptide Sequence: VMACGVTGSV SVALHPLVIL NISDHWIRMR SQEGRPVQVI GALIGKQEGR NIEVMNSFEL LSHTVEEKII IDKEYYYTKE EQFKQVFKEL EFLGWYTTGG PPDPSDIHVH KQVCEIIESP LFLKLNPMTK HTDLPVSVFE SVIDIINGEA TMLFAELTYT LATEEAERIG VDHVARMTAT GSGENSTVAE HLIAQHSAIK MLHSRVKLIL EYVKASEAGE VPFNHEILRE AYALCHCLPV LSTDKFKTDF YDQCN.

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COPS6
Applications ELISA, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone 2H5
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene COPS6
Gene Accession No. Q7L5N1
Gene Alias COP9 (constitutive photomorphogenic) homolog, subunit 6; COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana); COP9 (constitutive photomorphogenic), subunit 6; COP9 complex S6; COP9 constitutive photomorphogenic homolog subunit 6; COP9 signalosome complex subunit 6; COP9 signalosome complex subunit 6-like protein; COP9 signalosome subunit 6; cops6; CSN6; H_NH0506M12.12; hVIP; hypothetical protein LOC550465; JAB1-containing signalosome subunit 6; MOV34 homolog; MOV34 homolog, 34 kD; MOV34-34KD; Sgn3; SGN6; signalosome subunit 6; VIP/MOV34; Vpr-interacting protein; zgc:112075
Gene Symbols COPS6
Host Species Mouse
Immunogen COPS6 (AAH02520, 30 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10980
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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