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Invitrogen™ COPS6 Polyclonal Antibody
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Catalog No. PIPA560673
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100 μL
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PIPA560673 100 μL
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Catalog No. PIPA560673 Supplier Invitrogen™ Supplier No. PA560673
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Rabbit Polyclonal Antibody

Immunogen sequence: EVPFNHEILR EAYALCHCLP VLSTDKFKTD FYDQCNDVGL MAYLGTITKT CNTMNQFVNK FNVLYDRQGI GRRM Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COPS6
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COPS6
Gene Accession No. Q7L5N1
Gene Alias COP9 (constitutive photomorphogenic) homolog, subunit 6; COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana); COP9 (constitutive photomorphogenic), subunit 6; COP9 complex S6; COP9 constitutive photomorphogenic homolog subunit 6; COP9 signalosome complex subunit 6; COP9 signalosome complex subunit 6-like protein; COP9 signalosome subunit 6; cops6; CSN6; H_NH0506M12.12; hVIP; hypothetical protein LOC550465; JAB1-containing signalosome subunit 6; MOV34 homolog; MOV34 homolog, 34 kD; MOV34-34KD; Sgn3; SGN6; signalosome subunit 6; VIP/MOV34; Vpr-interacting protein; zgc:112075
Gene Symbols COPS6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COPS6. Recombinant protein control fragment (Product #RP-92864).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10980
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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