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Invitrogen™ COQ10B Polyclonal Antibody
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Catalog No. PIPA561138
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100 μL
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PIPA561138 100 μL
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Catalog No. PIPA561138 Supplier Invitrogen™ Supplier No. PA561138
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ARTGHTALRR VVSGCRPKSA TAAGAQAPVR NGRYLASCGI LMSRTLPLHT SILPKEICAR TFFKITAPLI NKRK Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 64%.

COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COQ10B
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COQ10B
Gene Accession No. Q9H8M1
Gene Alias 1500041J02Rik; 1700030I21Rik; 9530077A17Rik; AV002237; AW742641; coenzyme Q10 homolog B; coenzyme Q10 homolog B (S. cerevisiae); coenzyme Q10B; coenzyme Q-binding protein COQ10 homolog B, mitochondrial; COQ10B; RGD1359509
Gene Symbols COQ10B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COQ10B. Recombinant protein control fragment (Product #RP-96025).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80219
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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