Invitrogen™ COQ3 Monoclonal Antibody (6D5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524468

Catalog No. PIMA524468

Description

Peptide Sequence: IVPKGTHTWE KFVSPETLES ILESNGLSVQ TVVGMLYNPF SGYWHWSENT SLNYAAHAVK SRVQEHPASA EFVLKGETEE LQANACTNPA VHEKLKK.

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.

Specifications

• Antigen: COQ3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: COQ3
• Gene Alias: 2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone-10 3-methyltransferase; 3-demethylubiquinone-9 3-methyltransferase; 4732433J24; bA9819.1; C77934; Coenzyme Q (ubiquinone); coenzyme Q3 homolog methyltransferase; coenzyme Q3 homolog, methyltransferase; coenzyme Q3 homolog, methyltransferase (yeast); coenzyme Q3 methyltransferase; coenzyme Q3, methyltransferase; Coq3; DHHB methyltransferase; DHHBMT; DHHB-MT; DHHBMTASE; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; methyltransferase COQ3; polyprenyldihydroxybenzoate methyltransferase; Ubiquinone biosynthesis O-methyltransferase, mitochondrial; UG0215E05
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 51805
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 6D5
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9NZJ6
• Gene Symbols: COQ3
• Immunogen: COQ3 (NP_059117, 273 a.a. ~ 369 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ