COQ3 Mouse anti-Human, Clone: 6D5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524468
Peptide Sequence: IVPKGTHTWE KFVSPETLES ILESNGLSVQ TVVGMLYNPF SGYWHWSENT SLNYAAHAVK SRVQEHPASA EFVLKGETEE LQANACTNPA VHEKLKKUbiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
|COQ3 (NP_059117, 273 a.a. ∽ 369 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Western Blot|
|PBS with no preservative; pH 7.4|
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