Invitrogen™ COQ3 Polyclonal Antibody

Catalog No.	Quantity
PIPA556699	100 μL

Catalog No. PIPA556699 Supplier Invitrogen™ Supplier No. PA556699

Description

Rabbit Polyclonal Antibody

Immunogen sequence: WEKFVSPETL ESILESNGLS VQTVVGMLYN PFSGYWHWSE NTSLNYAAHA VKSRVQEHPA SAEFVLKGET EELQANACTN PAVHEKLKK Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 57%.

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.

Specifications

• Antigen: COQ3
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: COQ3
• Gene Accession No.: Q9NZJ6
• Gene Alias: 2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone-10 3-methyltransferase; 3-demethylubiquinone-9 3-methyltransferase; 4732433J24; bA9819.1; C77934; Coenzyme Q (ubiquinone); coenzyme Q3 homolog methyltransferase; coenzyme Q3 homolog, methyltransferase; coenzyme Q3 homolog, methyltransferase (yeast); coenzyme Q3 methyltransferase; coenzyme Q3, methyltransferase; Coq3; DHHB methyltransferase; DHHBMT; DHHB-MT; DHHBMTASE; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; methyltransferase COQ3; polyprenyldihydroxybenzoate methyltransferase; Ubiquinone biosynthesis O-methyltransferase, mitochondrial; UG0215E05
• Gene Symbols: COQ3
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human COQ3. Recombinant protein control fragment (Product #RP-94830).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51805
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG