Invitrogen™ CORIN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587872

Catalog No. PIPA587872

Description

Immunogen sequence: MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS; Positive Samples: Hela, HT-1080, Mouse heart, Mouse brain, Rat heart, Rat brain; Cellular Location: Cell membrane, Single-pass type II membrane protein, Single-pass type II membrane protein.

CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.

Specifications

• Antigen: CORIN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CORIN
• Gene Alias: ATC2; Atrial natriuretic peptide-converting enzyme; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; AV273130; Corin; corin, serine peptidase; CRN; EC 3.4.21; Heart-specific serine proteinase ATC2; low density lipoprotein receptor-related protein 4; low density lipoprotein-related protein 4; Lrp4; MGC119742; PEE5; pro-ANP-convertase; pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; TMPRSS10; Transmembrane protease serine 10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10699, 289596, 53419
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.99 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q80YN4, Q9Y5Q5, Q9Z319
• Gene Symbols: CORIN
• Immunogen: Recombinant protein (or fragments).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov