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Invitrogen™ Cortisol Monoclonal Antibody (BGN/C53)
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Catalog No. PIMA183090
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200 μg
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Catalog No. Quantity
PIMA183090 200 μg
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Catalog No. PIMA183090 Supplier Invitrogen™ Supplier No. MA183090
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Description

Mouse Monoclonal Antibody

Mouse anti cortisol monoclonal antibody, clone BGN/C53 recognizes cortisol, a glucocorticoid hormone synthesized from cholesterol by the adrenal cortex. It is released in response to pituitary adenocorticotrophic hormone (ACTH) which is, in turn, regulated by corticotrophin releasing factor (CRF).

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cortisol
Applications ELISA
Classification Monoclonal
Clone BGN/C53
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Host Species Mouse
Immunogen Synthetic corticosterone conjugated to BSA.
Purification Method Purified
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG3
Target Molecule Chemical
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