Invitrogen™ COTL1 Monoclonal Antibody (5C8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517060

Catalog No. PIMA517060

Description

MA5-17060 targets COTL1 in IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17060 immunogen is purified recombinant fragment of human COTL1 expressed in E. Coli. MA5-17060 detects COTL1 which has a predicted molecular weight of approximately 16kDa.

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

Specifications

• Antigen: COTL1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q14019
• Gene Symbols: Cotl1
• Immunogen: Purified recombinant fragment of human COTL1 expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5C8
• Conjugate: Unconjugated
• Gene: Cotl1
• Gene Alias: 1810074P22Rik; 2010004C08Rik; CLP; coactosin like F-actin binding protein 1; coactosin-like 1; coactosin-like 1 (Dictyostelium); coactosin-like F-actin binding protein 1; coactosin-like protein; coactosin-like protein {ECO:0000250; Cotl1; cotl1 {ECO:0000312; EMBL:AAI58747.1, ECO:0000312; FLJ43657; MGC137989 protein; MGC19733; RGD:1305498}; UniProtKB:Q14019}; Unknown (protein for MGC:63983); wu:fb08h08; zgc:63983
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23406
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid