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Epredia™ Lab Vision™ COX-1, Rabbit Polyclonal Antibody

Catalog No. RB10687R1 Shop All Epredia Products
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RB10687R1 1 mL
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Catalog No. RB10687R1 Supplier Epredia™ Supplier No. RB10687R1

Description

Ensure accurate and reproducible results in immunohistochemistry experiments with Epredia™ COX-1, Rabbit Polyclonal Antibody.

Cyclooxygenases 1 and 2 (COX-1, COX-2) are enzymes involved in the conversion of arichidonate to prostaglandins. COX-1 and COX-2 are very similar in structure and function, though they vary in expression. COX-1 is normally expressed in most cell types, whereas COX-2 expression is at low levels unless induced by hormonal stimuli. In some breast cancer and bladder carcinoma studies, COX-1 was expressed in the stroma cells adjacent to the tumors but not in tumor cells.

Host Species: Rabbit

Species Reactivity: Human. Others not tested.

Epitope: C-terminal

Immunogen: Synthetic peptide corresponding to C-terminal of human COX-1

Molecular Weight: 72 kDa

Positive Control: Esophagus

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen COX-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
Immunogen Synthetic peptide corresponding to C-terminal of human COX-1
Purification Method Esophagus
Quantity 1 mL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Prediluted
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