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Invitrogen™ COX10 Polyclonal Antibody
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Catalog No. PIPA577244
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100 μL
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PIPA577244 100 μL
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Catalog No. PIPA577244 Supplier Invitrogen™ Supplier No. PA577244
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene COX10
Gene Accession No. Q12887, Q8CFY5
Gene Alias 2410004F01Rik; AU042636; COX10; COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase; COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor; cytochrome c oxidase assembly homolog 10; cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein 10; cytochrome c oxidase subunit X; heme A: farnesyltransferase; heme O synthase; LOC691853; Protoheme IX farnesyltransferase, mitochondrial; similar to COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
Gene Symbols COX10
Host Species Rabbit
Immunogen Recombinant full length Human COX10.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1352, 691853, 70383
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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