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Invitrogen™ COX10 Polyclonal Antibody
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Catalog No. PIPA585407
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100 μL
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PIPA585407 100 μL
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Catalog No. PIPA585407 Supplier Invitrogen™ Supplier No. PA585407
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (92%), Zebrafish (81%), Xenopus laevis (84%), Pig (93%), Chicken (87%), Rhesus Monkey (97%), Bovine (92%). Positive Control: U87-MG, SK-N-SH, IMR-32, SK-N-AS. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene COX10
Gene Accession No. Q12887
Gene Alias 2410004F01Rik; AU042636; COX10; COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase; COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor; cytochrome c oxidase assembly homolog 10; cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein 10; cytochrome c oxidase subunit X; heme A: farnesyltransferase; heme O synthase; LOC691853; Protoheme IX farnesyltransferase, mitochondrial; similar to COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
Gene Symbols COX10
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human COX10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1352
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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