COX10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6447	Proteintech Group Inc 106112AP150UL	150 μL

Description

Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D); also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome.

Specifications

• Antigen: COX10
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q12887, Q8CFY5
• Gene ID (Entrez): 1352, 691853, 70383
• Immunogen: COX10 Fusion Protein Ag0930
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: COX10

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: COX10, Heme O synthase
• Gene Symbols: Cox10
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody