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Invitrogen™ COX11 Polyclonal Antibody
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Catalog No. PIPA560591
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100 μL
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PIPA560591 100 μL
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Catalog No. PIPA560591 Supplier Invitrogen™ Supplier No. PA560591
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DKPVIGISTY NIVPFEAGQY FNKIQCFCFE EQRLNPQEEV DMPVFFYIDP EFAEDPRMIK VDLITLSYTF FEAKEGHKLP VPG Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O2. Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex. COX11 contains a single transmembrane helix downstream of the N-terminal, mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain. The assembly of COX requires the delivery of metal cofactors. Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX11
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COX11
Gene Accession No. Q9Y6N1
Gene Alias 2010004I09Rik; Cox11; COX11 cytochrome c oxidase copper chaperone; COX11 homolog, cytochrome c oxidase assembly protein; COX11, cytochrome c oxidase copper chaperone; COX11P; cytochrome c oxidase assembly homolog 11; cytochrome c oxidase assembly protein 11; cytochrome c oxidase assembly protein COX11, mitochondrial; cytochrome c oxidase subunit 11
Gene Symbols COX11
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COX11. Recombinant protein control fragment (Product #RP-100211).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1353
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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