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Invitrogen™ COX15 Monoclonal Antibody (2D2)
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Catalog No. PIMA518633
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100 μg
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Catalog No. Quantity
PIMA518633 100 μg
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Catalog No. PIMA518633 Supplier Invitrogen™ Supplier No. MA518633
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Description

Mouse Monoclonal Antibody

Peptide Sequence: LTESGLSMVD WHLIKEMKPP TSQEEWEAEF QRYQQFPEFK ILNHDMTLTE FKFIWYMEYS H.

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX15
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2D2
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene COX15
Gene Accession No. Q7KZN9
Gene Alias 2900026G05Rik; CEMCOX2; COX15; COX15 cytochrome c oxidase assembly homolog; COX15 homolog, cytochrome c oxidase assembly protein; COX15, cytochrome c oxidase assembly homolog; cytochrome c oxidase assembly homolog 15; cytochrome c oxidase assembly homolog 15 (yeast); cytochrome c oxidase assembly protein 15; cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15
Gene Symbols COX15
Host Species Mouse
Immunogen COX15 (NP_510870, 92 a.a. ~ 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1355
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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