Invitrogen™ COX18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550492

Catalog No. PA550492

Description

The antibody detects endogenous levels of total COX18 protein.

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.

Specifications

• Antigen: COX18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cox18
• Gene Alias: BC038311; COX18; COX18 cytochrome c oxidase assembly factor; COX18 cytochrome c oxidase assembly homolog; COX18, cytochrome c oxidase assembly factor; COX18Hs; cytochrome c oxidase assembly factor COX18; cytochrome c oxidase assembly homolog 18; cytochrome c oxidase assembly protein 18; Cytochrome c oxidase assembly protein COX18, mitochondrial; mitochondrial inner membrane protein COX18; Oxa1l2; RGD1559547
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 285521
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8N8Q8
• Gene Symbols: Cox18
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cytochrome c oxidase assembly homolog 18 (yeast).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG