COX2/ Cyclooxygenase 2 Mouse anti-Human, Mouse, Clone: 3G2B9, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 663511IG150UL

Catalog No. 50-173-6782

Description

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Specifications

• Antigen: COX2/ Cyclooxygenase 2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35354, Q05769
• Gene Symbols: PTGS2
• Immunogen: COX2/ Cyclooxygenase 2 Fusion Protein Ag24721
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 3G2B9
• Conjugate: Unconjugated
• Gene: PTGS2
• Gene Alias: COX 2, COX2, COX2/ Cyclooxygenase 2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 19225, 5743
• Content And Storage: -20°C
• Form: Liquid