Invitrogen™ COX6C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106557

Catalog No. PIPA5106557

Description

Antibody detects endogenous levels of total COX6C.

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Specifications

• Antigen: COX6C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COX6C
• Gene Alias: COVIc; Cox6c; Cox6c2; COX-VIc; cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase polypeptide VIc-2; cytochrome c oxidase subunit 6C; Cytochrome c oxidase subunit 6C-2; cytochrome c oxidase subunit VIc; cytochrome c oxidase subunit VIc preprotein; cytochrome c oxidase, subunit VIc; cytochrome oxidase subunit VIc; EC 1.9.3.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12864, 1345, 54322
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09669, P11951, Q9CPQ1
• Gene Symbols: COX6C
• Immunogen: A synthesized peptide derived from human COX6C(Accession P09669), corresponding to amino acid residues R20-I70.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov