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Invitrogen™ COX8C Polyclonal Antibody
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Catalog No. PIPA551830
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100 μL
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PIPA551830 100 μL
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Catalog No. PIPA551830 Supplier Invitrogen™ Supplier No. PA551830
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPLLRGRCPA RRHYRRLALL GLQPAPRFAH SGPPRQRPLS AAE Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 35%.

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport. This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COX8C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COX8C
Gene Accession No. Q7Z4L0
Gene Alias 1700007F21Rik; COX VIII-3; COX8-3; Cox8c; COXVIII-3; cytochrome c oxidase polypeptide 8; Cytochrome c oxidase polypeptide 8 isoform 3; cytochrome c oxidase polypeptide VIII; Cytochrome c oxidase polypeptide VIII isoform 3; Cytochrome c oxidase subunit 8-3; cytochrome c oxidase subunit 8C; cytochrome c oxidase subunit 8C, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIC
Gene Symbols COX8C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COX8C. Recombinant protein control fragment (Product #RP-89115).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 341947
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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