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Tocris Bioscience™ CP 673451
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Catalog No. 599310
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10 mg
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Catalog No. Quantity
59-931-0 10 mg
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Catalog No. 59-931-0 Supplier Tocris Bioscience™ Supplier No. 5993/10
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Description

Potent and selective PDGFR inhibitor

CP 673451 is a potent and selective PDGFR inhibitor (IC50 values are 1 and 10 nM for PDGFR-β and -α respectively). Selective for PDGFR kinase over a range of related kinases. Inhibits PDGFR-β phosphorylation in glioblastoma xenografts and PDGF-induced angiogenesis in mice.

Specifications

Chemical Name or Material 1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine
CAS 343787-29-1
Quantity 10 mg
Solubility Soluble to 100mM in water and to 100mM in DMSO
Molecular Formula C24H27N5O2
Formula Weight 417.5
Physical Form Solid
Color White
Product Type Bioactive Small Molecule
Purity >98%

For Research Use Only.

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