Invitrogen™ CP110 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142843

Catalog No. PIPA5142843

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001185951.1; NP_055526.3). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt].

Specifications

• Antigen: CP110
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCP110
• Gene Alias: 6330503K22Rik; AA415922; AI427129; AW557948; CCP110; centriolar coiled coil protein 110; centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110; centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; Kiaa0419; RGD1310509
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 9738
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43303
• Gene Symbols: CCP110
• Immunogen: Peptide with sequence CEKSLARIQEAS (aa 8-19).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG