Invitrogen™ CP110 Recombinant Rabbit Monoclonal Antibody (HL2312)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550487

Catalog No. FEMA550487

Description

CP110 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt].

Specifications

• Antigen: CP110
• Classification: Recombinant Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O43303, Q7TSH4
• Gene Symbols: CCP110
• Immunogen: Recombinant fragmemt of human CP110.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL2312
• Conjugate: Unconjugated
• Gene: CCP110
• Gene Alias: 6330503K22Rik; AA415922; AI427129; AW557948; CCP110; centriolar coiled coil protein 110; centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110; centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; Kiaa0419; RGD1310509
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 101565, 361634, 9738
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid