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Invitrogen™ CPB2 Polyclonal Antibody
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Catalog No. PIPA5109580
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Quantity:
100 μL
Catalog No. Quantity
PIPA5109580 100 μL
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Catalog No. PIPA5109580

Supplier: Invitrogen™ PA5109580

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASASYYEQYH SLNEIYSWIE FITERHPDML TKIHIGSSFE KYPLYVLKVS GKEQAAKNAI WIDCGIHARE WISPAFCLWF IGHITQFYGI IGQYTNLLRL VDFYVMPVVN VDGYDYSWKK NRMWRKNRSF YANNHCIGTD LNRNFASKHW CEEGASSSSC SETYCGLYPE SEPEVKAVAS FLRRNINQIK AYISMHSYSQ HIVFPYSYTR SKSKDHEELS LVASEAVRAI EKTSKNTRYT HGHGSETLYL A.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CPB2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CPB2
Gene Accession No. Q96IY4
Gene Alias 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Symbols CPB2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 115-365 of human CPB2 (NP_001863.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1361
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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