Invitrogen™ CPB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109580

Catalog No. PIPA5109580

Description

Immunogen sequence: ASASYYEQYH SLNEIYSWIE FITERHPDML TKIHIGSSFE KYPLYVLKVS GKEQAAKNAI WIDCGIHARE WISPAFCLWF IGHITQFYGI IGQYTNLLRL VDFYVMPVVN VDGYDYSWKK NRMWRKNRSF YANNHCIGTD LNRNFASKHW CEEGASSSSC SETYCGLYPE SEPEVKAVAS FLRRNINQIK AYISMHSYSQ HIVFPYSYTR SKSKDHEELS LVASEAVRAI EKTSKNTRYT HGHGSETLYL A.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Specifications

• Antigen: CPB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CPB2
• Gene Alias: 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1361
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96IY4
• Gene Symbols: CPB2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 115-365 of human CPB2 (NP_001863.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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