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CPB2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987821
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100 μL
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50-198-7821 100 μL
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Catalog No. 50-198-7821 Supplier Bioss Supplier No. BS7547R
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Rabbit Polyclonal Antibody

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Specifications

Antigen CPB2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CPB2
Gene Accession No. Q96IY4
Gene Alias 1110032P04Rik; 4930405E17Rik; AI255929; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; Carboxypeptidase R; Carboxypeptidase U; CPB2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Symbols CPB2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CPB2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1361
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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