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Tocris Bioscience™ CPI 203
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Catalog No. 533110
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10 mg
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Catalog No. Quantity
53-311-0 10 mg
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Catalog No. 53-311-0 Supplier Tocris Bioscience™ Supplier No. 5331/10
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Description

BET bromodomain inhibitor; arrests cell cycle at G1 phase

CPI 203 is a BET bromodomain inhibitor. Downregulates Myc expression, causes G1 cell cycle arrest and attenuates cell proliferation in human pancreatic neuroendocrine tumors. Arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Also enhances the antitumor effect of rapamycin (Cat. No. 1292) in vitro and attenuates rapamycin induced Akt activation. Also enhances fibroblast reprogramming to hiPSCs at low concentration. Orally bioavailable.

Specifications

Quantity 10 mg
Product Type CPI 203
Purity >98%
Molecular Weight (g/mol) 399.9
Inhibitors CPI 203

For Research Use Only

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