CPI17 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7351	150 μL

Catalog No. 50-172-7351 Supplier Proteintech Group Inc Supplier No. 116581AP150UL

Description

Rabbit Polyclonal Antibody

CPI-17 is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. CPI-17 was originally identified as a PKC-potentiated inhibitory protein of protein phosphatase-1, which is domitly expressed in smooth muscle. Phosphorylation at Threonine 38, in vitro, by PKC or Rho-kinase enhances the inhibitory potency toward myosin phosphatase. CPI-17 is also phosphorylated at Threonine 38 by protein kinase N and might be involved in the calcium sensitization of smooth muscle contraction as a downstream effector of Rho and/or arachidonic acid. CPI-17 is dually phosphorylated at Serine 12 and Threonine 38 by a MYPT-associated kinase, M110 kinase.

Specifications

• Antigen: CPI17
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PPP1R14A
• Gene Accession No.: Q96A00
• Gene Alias: CPI 17, CPI17, PPP1INL, PPP1R14A
• Gene Symbols: PPP1R14A
• Host Species: Rabbit
• Immunogen: CPI17 Fusion Protein Ag2237
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 94274
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG