Invitrogen™ CPOX Polyclonal Antibody

Catalog No.	Quantity
PIPA596257	100 μL

Catalog No. PIPA596257

Supplier: Invitrogen™ PA596257

Description

Rabbit Polyclonal Antibody

Immunogen sequence: TSLGRPEEEE DELAHRCSSF MAPPVTDLGE LRRRPGDMKT KMELLILETQ AQVCQALAQV DGGANFSVDR WERKEGGGGI SCVLQDGCVF EKAGVSISVV HGNLSEEAAK QMRSRGKVLK TKDGKLPFCA MGVSSVIHPK NPHAPTIHFN YRYFEVEEAD GNKQWWFGGG CDLTPTYLNQ EDAVHFHRTL KEACDQHGPD LYPKFKKWCD DYFFIAHRGE RRGIGGIFFD DLDSPSKEEV FRFVQSCARA VVPSYIPLVK KHCDDSFTPQ EKLWQQLRRG RYVEFNLLYD RGTKFGLFTP GSRIESILMS LPLTARWEYM HSPSENSKEA EILEVLRHPR DWVR; Positive Samples: HeLa, A375, HepG2, A-549, Mouse liver, Rat liver; Cellular Location: Mitochondrion intermembrane space.

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Specifications

• Antigen: CPOX
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 2.11 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CPOX
• Gene Accession No.: P36551, P36552, Q3B7D0
• Gene Alias: cac; clone 560; coprogen oxidase; Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX); coproporphyrinogen oxidase; coproporphyrinogenase; coproporphyrinogen-III oxidase, mitochondrial; COX; CPO; Cpox; cpox {ECO:0000312; CPX; EMBL:AAI07665.1}; HCP; nct; oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
• Gene Symbols: CPOX
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_0000883).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12892, 1371, 304024
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG