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Invitrogen™ CPS1 Polyclonal Antibody
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Catalog No. PIPA5109584
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100 μL
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PIPA5109584 100 μL
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Catalog No. PIPA5109584 Supplier Invitrogen™ Supplier No. PA5109584
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IKNVVSGKTS ACFEPSLDYM VTKIPRWDLD RFHGTSSRIG SSMKSVGEVM AIGRTFEESF QKALRMCHPS IEGFTPRLPM NKEWPSNLDL RKELSEPSST RIYAIAKAID DNMSLDEIEK LTYIDKWFLY KMRDILNMEK TLKGLNSESM TEETLKRAKE IGFSDKQISK CLGLTEAQTR ELRLKKNIHP WVKQIDTLAA EYPSVTNYLY VTYNGQEHDV N.

The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CPS1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CPS1
Gene Accession No. P07756, P31327, Q8C196
Gene Alias 4732433M03Rik; carbamoyl-phosphate synthase (ammonia); carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthase 1; carbamoyl-phosphate synthase 1, mitochondrial; carbamoyl-phosphate synthetase 1; carbamoyl-phosphate synthetase 1, mitochondrial; carbamoylphosphate synthetase I; carbamoyl-phosphate synthetase I; carbamyl phosphate synthetase I; carboamyl-phosphate synthetase 1; cps; CPS1; CPSase I; CPSASE1; CPSI; D1Ucla3; PHN
Gene Symbols CPS1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human CPS1 (NP_0018662).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1373, 227231, 497840
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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