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Invitrogen™ CPSF1 Polyclonal Antibody
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Catalog No. PIPA567022
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PIPA567022 100 μL
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Catalog No. PIPA567022 Supplier Invitrogen™ Supplier No. PA567022
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AISLNITQKVH PVIWSLTSLP FDCTQALAVP KPIGGVVVFA VNSLLYLNQS VPPYGVALNS LTTGTTAFPL RT Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.

Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CPSF1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cpsf1
Gene Accession No. Q10570
Gene Alias cleavage and polyadenylation specific factor 1; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF1; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor
Gene Symbols Cpsf1
Host Species Rabbit
Immunogen Recombinant Human CPSF1. Recombinant protein control fragment (Product #RP-107662).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29894
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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