Invitrogen™ CPT1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106270

Catalog No. PIPA5106270

Description

Antibody detects endogenous levels of total CPT1A.

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CPT1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cpt1a
• Gene Alias: C730027G07; carnitine O-palmitoyltransferase; carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyl transferase I isoform; Carnitine palmitoyltransferase 1 alpha, liver isoform; carnitine palmitoyltransferase 1, liver; carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase 1a, liver; carnitine palmitoyltransferase I, liver; CPT 1; CPT I; Cpt1; Cpt-1; CPT1 L; CPT1A; CPT1-L; CPTI; CPT-Ia; CPTI-L; L-CPT I; L-CPT1; mitochondrial carnitine palmitoyltransferase 1A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12894, 1374, 25757
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P32198, P50416, P97742
• Gene Symbols: Cpt1a
• Immunogen: A synthesized peptide derived from human CPT1A(Accession P50416), corresponding to amino acid residues R601-S651.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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