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Invitrogen™ CRACC Polyclonal Antibody
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Catalog No. PIPA566409
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100 μL
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PIPA566409 100 μL
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Catalog No. PIPA566409 Supplier Invitrogen™ Supplier No. PA566409
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGPVKELVGSV GGAVTFPLKS KVKQVDSIVW TFNTTPLVTI QPEGGTIIVT QNRNRERVDF PDGGYSLKLS KLKKNDSGIY YVGIYSSSL Highest antigen sequence identity to the following orthologs - mouse 49%, rat 43%.

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRACC
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLAMF7
Gene Accession No. Q9NQ25
Gene Alias 19A; 19A24; 19A24 protein; 4930560D03Rik; CD2 subset 1; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; CD319; CRACC; CS1; Leukocyte cell-surface antigen; membrane protein FOAP-12; Novel Ly9; novel LY9 (lymphocyte antigen 9) like protein; protein 19A; RGD1560190; SLAM family member 7; SLAMF7; UNQ576/PRO1138
Gene Symbols SLAMF7
Host Species Rabbit
Immunogen Recombinant Human CRACC. Recombinant protein control fragment (Product #RP-105198).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57823
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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