Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 69485

Tocris Bioscience™ CRBN-6-5-5-VHL
GREENER_CHOICE

Catalog No. 69485
Change view
Click to view available options
Quantity:
5 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
69-485 5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 69-485 Supplier Tocris Bioscience™ Supplier No. 6948/5
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent and selective cereblon Degrader (PROTAC™); cell-permeable

Potent and selective cereblon Degrader (PROTAC™) (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material (2 S,4 R)-1-((2 S)-2-(5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS 2362575-45-7
Quantity 5 mg
Solubility Soluble to 100mM in DMSO
Target Active Degraders
Molecular Formula C51H69N7O10S
Formula Weight 972.21
Physical Form Solid
Color Yellow
Product Type Degrader
Purity 96%
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.