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CRBN Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981609
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100 μL
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50-198-1609 100 μL
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Catalog No. 50-198-1609 Supplier Bioss Supplier No. BS11716R
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Description

Rabbit Polyclonal Antibody

CRBN, a member of the Lon protease protein family, plays a role in brain development. It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain.

Specifications

Antigen CRBN
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CRBN
Gene Accession No. Q96SW2
Gene Alias 2610203G15Rik; 2900045O07Rik; AD-006; AF229032; AW108261; cereblon; CRBN; DKFZp781K0715; MGC27358; MRT2; MRT2A; novel lethal; piL; Protein cereblon; Protein PiL; protein x 0001
Gene Symbols CRBN
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CRBN .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51185
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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