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Tocris Bioscience™ CRBN5-SNAP2-1C-PIP

Catalog No. 88915
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88-915 5 mg
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Catalog No. 88-915 Supplier Tocris Bioscience™ Supplier No. 8891/5
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Description

Degrader (PROTAC™) of SNAP-tag™ labeled fusion proteins

CRBN5-SNAP2-1C-PIP is a Degrader (PROTAC™) of SNAP-tag™ labeled fusion proteins (Dmax = 75% at 1 μM). CRBN5-SNAP2-1C-PIP recruits cereblon E3 ligase to induce the degradation of SNAP-fusion proteins. PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license. SNAP-tag is a trademark of New England BioLabs, Inc.

Specifications

Chemical Name or Material N-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-2-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)acetamide
Quantity 5 mg
Target Active Degraders
Molecular Formula C32H32ClN7O6
Purity 0.97
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