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Invitrogen™ CKMT1A Polyclonal Antibody
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Catalog No. PIPA560387
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100 μL
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PIPA560387 100 μL
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Catalog No. PIPA560387 Supplier Invitrogen™ Supplier No. PA560387
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YLIDCERRLE RGQDIRIPTP VIHTKH Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 81%.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CKMT1A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CKMT1A
Gene Accession No. P12532
Gene Alias Acidic-type mitochondrial creatine kinase; CKMT; Ckmt1; CKMT1A; Ckmt1b; Creatine kinase U-type, mitochondrial; creatine kinase, mitochondrial 1 (ubiquitous); creatine kinase, mitochondrial 1, ubiquitous; creatine kinase, mitochondrial 1A; creatine kinase, mitochondrial 1B; mia-CK; mi-CK; Mt-CK; ScCKmit; UbCKmit; Ubiquitous mitochondrial creatine kinase; U-MtCK
Gene Symbols CKMT1A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CKMT1A. Recombinant protein control fragment (Product #RP-99584).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 548596
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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