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Invitrogen™ CREM Polyclonal Antibody
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Catalog No. PIPA5120930
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100 μL
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PIPA5120930 100 μL
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Catalog No. PIPA5120930 Supplier Invitrogen™ Supplier No. PA5120930
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Description

Rabbit Polyclonal Antibody

Positive test controls include: 293T, K-562, Mouse testis, Rat testis. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: MSKCARKKYI KTNPRQMTME TVESQHDGSI TASLTESKSA HVQTQTGQNS IPALAQVAAI AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP.

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CREM
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CREM
Gene Accession No. P27699, Q03060, Q03061
Gene Alias cAMP response element modulator; cAMP responsive element moderator; cAMP responsive element modulator; cAMP-responsive element modulator; CRE modulator; CREM; CREM 2alpha-b protein; CREM 2beta-a protein; CREM-2; hCREM-2; ICER; ICERI; inducible cAMP early repressor; inducible cAMP early repressor ICER; inducible cyclic AMP early repressor; MGC111110; MGC17881; MGC41893; OTTHUMP00000019443
Gene Symbols CREM
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12916, 1390, 25620
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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