Invitrogen™ CREM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529927

Catalog No. PIPA529927

Description

Recommended positive controls: NT2D1, Neuro2A, GL261, PC-12, Rat2. Predicted reactivity: Mouse (93%), Rat (91%), Dog (86%), Chicken (88%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

Specifications

• Antigen: CREM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CREM
• Gene Alias: cAMP response element modulator; cAMP responsive element moderator; cAMP responsive element modulator; cAMP-responsive element modulator; CRE modulator; CREM; CREM 2alpha-b protein; CREM 2beta-a protein; CREM-2; hCREM-2; ICER; ICERI; inducible cAMP early repressor; inducible cAMP early repressor ICER; inducible cyclic AMP early repressor; MGC111110; MGC17881; MGC41893; OTTHUMP00000019443
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12916, 1390, 25620
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.31 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P27699, Q03060, Q03061
• Gene Symbols: CREM
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CREM. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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