CRF Monoclonal Antibody (5D5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA183085

Catalog No. MA183085

Description

Predicted to react with rat based on sequence homology. This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase. Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for this product is human hypothalamus. Mouse anti Human corticotrophin-releasing factor antibody, clone 5D5 recognizes human corticotropin-releasing factor (CRF), a secreted hormone which regulates the release of corticotropin from the pituitary.

Corticotropin Releasing Factor (CRF), a 41 amino acids neuropeptide, belongs to a family of structurally related peptides including urocortin, sauvagine and urotensin I. CRF is critical in the regulation of the pituitary-adrenal gland axis, and in endocrine, autonomic and behavioral responses to stress. CRF is widely distributed in the brain and peripheral nervous system with the highest levels in the hypothalamic paraventricular nucleus.

Specifications

• Antigen: CRF
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with <0.1% sodium azide
• Gene Accession No.: P06850
• Gene Symbols: CRH
• Immunogen: Synthetic human corticotropin factor
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: 5D5
• Conjugate: Unconjugated
• Gene: CRH
• Gene Alias: Corticoliberin; corticotropin releasing factor; corticotropin releasing hormone; corticotropin releasing hormone receptor 2; corticotropin-releasing factor; Corticotropin-releasing factor receptor 2; corticotropin-releasing hormone; Corticotropin-releasing hormone receptor 2; CRF; CRF2; CRF2 receptor, beta isoform; CRF2R; CRFR2; CRF-R-2; CRF-RB; CRH; CRH receptor 2 variant B; CRH1; CRH2R; CRHR2; CRH-R2; CRH-R-2; Gm1347; HM-CRF
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1392
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid