CRHR1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA527121

Catalog No. PIPA527121

Description

Recommended positive controls: Mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Rabbit (100%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.

Specifications

• Antigen: CRHR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CRHR1
• Gene Alias: corticotrophin releasing hormone receptor 1; corticotropin releasing hormone 1; corticotropin releasing hormone receptor 1; corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; corticotropin-releasing hormone receptor 1; CRF 1 receptor; Crf receptor 1; Crf type 1; CRF1; Crf1 receptor; CRFR; CRF-R; CRFR1; CRF-R1; CRF-R-1; CRFR-1; CRF-R1alpha; CRH receptor 1; CRH receptor subtype-1 isoform-3; Crhr; CRH-R 1; CRHR1; CRH-R1; CRH-R-1; CRHR1f; CRH-R1h; CRHR1L; seven transmembrane helix receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12921, 1394
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P34998, P35347
• Gene Symbols: CRHR1
• Immunogen: Synthetic peptide corresponding to a region within amino acids 53 and 147 of Human CRFR1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG