Invitrogen™ CRHR1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518625

Catalog No. PIPA518625

Description

This antibody is predicted to react with bovine, canine, human, ovine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1,000.

Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.

Specifications

• Antigen: CRHR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CRHR1
• Gene Alias: corticotrophin releasing hormone receptor 1; corticotropin releasing hormone 1; corticotropin releasing hormone receptor 1; corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; corticotropin-releasing hormone receptor 1; CRF 1 receptor; Crf receptor 1; Crf type 1; CRF1; Crf1 receptor; CRFR; CRF-R; CRFR1; CRF-R1; CRF-R-1; CRFR-1; CRF-R1alpha; CRH receptor 1; CRH receptor subtype-1 isoform-3; Crhr; CRH-R 1; CRHR1; CRH-R1; CRH-R-1; CRHR1f; CRH-R1h; CRHR1L; seven transmembrane helix receptor
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 12921, 1394
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P34998, P35347
• Gene Symbols: CRHR1
• Immunogen: Synthetic peptide sequence (KLYYDNEKCWFGKR) corresponding to the internal amino acids of CRHR1 (aa 279-292).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG