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Invitrogen™ CRIM2 Polyclonal Antibody
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Catalog No. PIPA534411
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100 μg
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Catalog No. Quantity
PIPA534411 100 μg
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Catalog No. PIPA534411 Supplier Invitrogen™ Supplier No. PA534411
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-34411 can be used with blocking peptide PEP-1453.

CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRIM2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene KCP
Gene Accession No. Q3U492, Q6ZWJ8
Gene Alias AW060220; CRIM2; CRIM-2; cysteine rich BMP regulator 2 (chordin like); cysteine rich BMP regulator 2 (chordin-like); cysteine-rich BMP regulator 2; Cysteine-rich motor neuron 2 protein; Gm793; KCP; Kcp1; KCP-1; kielin; kielin/chordin-like protein; Kielin/chordin-like protein 1; NET67; RGD1561119
Gene Symbols KCP
Host Species Rabbit
Immunogen A 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 296952, 333088, 375616
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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