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Invitrogen™ Cripto Polyclonal Antibody
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Catalog No. PIPA5116016
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100 μL
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PIPA5116016 100 μL
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Catalog No. PIPA5116016 Supplier Invitrogen™ Supplier No. PA5116016
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TDGF1.

Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cripto
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene TDGF1
Gene Accession No. P13385, P51865
Gene Alias CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
Gene Symbols TDGF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TDGF1(Accession P13385), corresponding to amino acid residues A96-L146.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21667, 680246, 6997
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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