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Invitrogen™ CRISP2 Polyclonal Antibody
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Catalog No. PIPA583187
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100 μL
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PIPA583187 100 μL
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Catalog No. PIPA583187 Supplier Invitrogen™ Supplier No. PA583187
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GCPDDCDKGL CTNSCQYQDL LSNCDSLKNT AGCEHELLKE KCKATCLCEN Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 72%.

The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRISP2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CRISP2
Gene Accession No. P16562
Gene Alias Cancer/testis antigen 36; CRISP2; CRISP-2; Crisp2l; CT36; cysteine rich secretory protein 2; cysteine-rich secretory protein 2; cysteine-rich secretory protein 2-like; GAPDL5; glyceraldehyde-3-phosphate dehydrogenase-like 5; MGC111136; OTTHUMP00000016589; testicular tissue protein Li 43; testis specific gene 1; testis specific protein 1; testis specific protein 1 (probe H4-1 p3-1); testis-specific protein TPX-1; TPX1; Tpx-1; TSP1
Gene Symbols CRISP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CRISP2. Recombinant protein control fragment (Product #RP-94742).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7180
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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