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Crizotinib, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
877399-52-5
C21H22Cl2FN5O
450.34
MFCD12407409
KTEIFNKAUNYNJU-UHFFFAOYNA-N
crizotinib, xalkori, r-crizotinib, crizotinibum, 3-1r-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-4-piperidinyl-1h-pyrazol-4-yl-2-pyridinamine, xalkori tn, r-3-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-piperidin-4-yl-1h-pyrazol-4-yl pyridin-2-amine, crizotinib pf-02341066, 3-1r-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-piperidin-4-yl-1h-pyrazol-4-yl pyridin-2-amine, crizotinib pf-2341066
11626560
CHEBI:64310
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine
CC(OC1=C(N)N=CC(=C1)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl
This item is not returnable. View return policy
877399-52-5
C21H22Cl2FN5O
450.34
MFCD12407409
KTEIFNKAUNYNJU-UHFFFAOYNA-N
crizotinib, xalkori, r-crizotinib, crizotinibum, 3-1r-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-4-piperidinyl-1h-pyrazol-4-yl-2-pyridinamine, xalkori tn, r-3-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-piperidin-4-yl-1h-pyrazol-4-yl pyridin-2-amine, crizotinib pf-02341066, 3-1r-1-2,6-dichloro-3-fluorophenyl ethoxy-5-1-piperidin-4-yl-1h-pyrazol-4-yl pyridin-2-amine, crizotinib pf-2341066
11626560
CHEBI:64310
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine
CC(OC1=C(N)N=CC(=C1)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl

Potent c-MET/ALK inhibitor

Potent inhibitor of c-MET and anaplastic lymphoma kinase (ALK) (cell IC50 values are 8.0 and 20 nM respectively). Selective for c-MET and ALK against >120 different kinases. Displays antitumor efficacy in multiple tumor models; inhibits c-MET-dependent proliferation, migration and invasion of human tumor cells in vitro. Orally bioavailable.
Quantity 10mg
Assay Percent Range >99%
Formula Weight 450.34
Chemical Name or Material Crizotinib

Recommended Storage : Store at +4°C