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Invitrogen™ Crk Polyclonal Antibody
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Catalog No. PIPA5115050
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100 μL
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PIPA5115050 100 μL
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Catalog No. PIPA5115050 Supplier Invitrogen™ Supplier No. PA5115050
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Crk p38.

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Crk
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Crk
Gene Accession No. P46108, P47811, P70618, Q16539, Q63768, Q64010
Gene Alias Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; CRK; CRK proto-oncogene, adaptor protein; CRK1; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; CSBP2; CSPB1; CT-10 related kinase 3; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; I79_016605; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38a; p38ALPHA; p38-alpha; p38alpha Exip; p38Hog; p38MAPK; PRKM14; PRKM15; Proto-oncogene c-Crk; reactive kinase; RK; SAPK2A; stress-activated protein kinase 2A; tRNA synthetase cofactor p38; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian); v-crk sarcoma virus CT10 oncogene-like protein
Gene Symbols Crk, Mapk14
Host Species Rabbit
Immunogen A synthesized peptide derived from human CRK(Accession P46108), corresponding to amino acid residues L200-A250.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12928, 1398, 1432, 26416, 54245, 81649
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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