Invitrogen™ CRMP3 Monoclonal Antibody (1F5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521089

Catalog No. PIMA521089

Description

Peptide Sequence: VTPGAGRFVP RKTFPDFVYK RIKARNRLAE IHGVPRGLYD GPVHEVMVPA KPGSGAPARA SCPGKISVPP VRNLHQSGFS LSGSQADDHI ARRTAQKIM.

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.

Specifications

• Antigen: CRMP3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: O14531
• Gene Symbols: DPYSL4
• Immunogen: DPYSL4 (NP_006417, 461 a.a. ~ 559 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 1F5
• Conjugate: Unconjugated
• Gene: DPYSL4
• Gene Alias: AI173505; Collapsin response mediator protein 3; CRMP3; CRMP-3; dihydropyrimidinase like 4; dihydropyrimidinase-like 4; dihydropyrimidinase-related protein 4; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10570
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid