Invitrogen™ CRMP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536585

Catalog No. PIPA536585

Description

This antibody detects endogenous protein at a molecular weight of 50 kDa. Purity is >95% by SDS-PAGE.

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.

Specifications

• Antigen: CRMP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DPYSL4
• Gene Alias: AI173505; Collapsin response mediator protein 3; CRMP3; CRMP-3; dihydropyrimidinase like 4; dihydropyrimidinase-like 4; dihydropyrimidinase-related protein 4; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10570, 25417, 26757
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.2
• Gene Accession No.: O14531, O35098, Q62951
• Gene Symbols: DPYSL4
• Immunogen: Synthetic peptide corresponding to amino acids 111-160 of human CRMP-3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG