Invitrogen™ CRMP3 Recombinant Rabbit Monoclonal Antibody (8N2S10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542614

Catalog No. PIMA542614

Description

Positive test controls include: C6. Immunogen sequence: MSFQGKKSIP RITSDRLLIR GGRIVNDDQS FYADVHVEDG LIKQIGENLI VPGGIKTIDA HGLMVLPGGV DVHTRLQMPV LGMTPADDFC QGTKAALAGG.

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.

Specifications

• Antigen: CRMP3
• Classification: Recombinant Monoclonal
• Concentration: 0.33 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q62951
• Gene Symbols: DPYSL4
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRMP3/DPYSL4 (O14531).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 8N2S10
• Conjugate: Unconjugated
• Gene: DPYSL4
• Gene Alias: AI173505; Collapsin response mediator protein 3; CRMP3; CRMP-3; dihydropyrimidinase like 4; dihydropyrimidinase-like 4; dihydropyrimidinase-related protein 4; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25417
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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