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Invitrogen™ CRMP5 Polyclonal Antibody
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Catalog No. PIPA584896
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100 μL
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PIPA584896 100 μL
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Catalog No. PIPA584896 Supplier Invitrogen™ Supplier No. PA584896
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CPIYLVNVSS ISAGDVIAAA KMQGKVVLAE TTTAHATLTG LHYYHQDWSH AAAYVTVPPL RLDTNTSTYL MSLLANDTLN IVASDH Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRMP5
Applications Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DPYSL5
Gene Accession No. Q9BPU6
Gene Alias collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP3-associated molecule; Crmp5; CRMP-5; dihydropyrimidinase like 5; dihydropyrimidinase-like 5; dihydropyrimidinase-related protein 5; Dpysl5; DRP-5; Ulip6; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6
Gene Symbols DPYSL5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DPYSL5. Recombinant protein control fragment (Product #RP-105561).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56896
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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