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Invitrogen™ CRMP5 Recombinant Rabbit Monoclonal Antibody (5L4S8)
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Catalog No. PIMA542815
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100 μL
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PIMA542815 100 μL
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Catalog No. PIMA542815 Supplier Invitrogen™ Supplier No. MA542815
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: SH-SY5Y, Mouse testis, Rat testis. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: RSFPDTVYKK LVQREKTLKV RGVDRTPYLG DVAVVVHPGK KEMGTPLADT PTRPVTRHGG MRDLHESSFS LSGSQIDDHV PKRASARILA PPGGRSSGIW.

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRMP5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 5L4S8
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DPYSL5
Gene Accession No. Q9BPU6, Q9EQF6, Q9JHU0
Gene Alias collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP3-associated molecule; Crmp5; CRMP-5; dihydropyrimidinase like 5; dihydropyrimidinase-like 5; dihydropyrimidinase-related protein 5; Dpysl5; DRP-5; Ulip6; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6
Gene Symbols DPYSL5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CRMP5/DPYSL5 (Q9BPU6).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56896, 65208, 65254
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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